Dr. Todd F. Kagawa is a researcher in the Department of Biological Sciences at the University of Limerick (UL), where his work focuses on protease biochemistry, particularly C5a peptidases from Streptococcus species, and their potential as therapeutic agents in inflammatory conditions.
His structural and kinetic studies of the C5a-peptidase enzyme revealed how substrate binding and exosite interactions can be engineered for enhanced specificity and activity. Dr Kagawa’s contributions support UL spin-out ventures in immune-modulatory therapeutics and contribute to the broader mission of translating fundamental enzymology into clinical innovation.
Immunomodulatory Enzyme Therapy
Engineering of immunomodulatory enzymes for the treatment of skin diseases
Lead: Prof. Jakki Cooney, Prof. Padraic Fallon, Dr. Todd Kagawa
